View Monkeypox Symptoms Background. The main difference between symptoms of smallpox and monkeypox is that monkeypox causes lymph nodes to swell (lymphadenopathy) while smallpox does not. Monkeypox begins with fever, headache, muscle aches, and exhaustion.
Symptoms of the disease are similar to smallpox but are milder. See full list on who.int Captive animals that are potentially infected with monkeypox should be isolated from other animals and placed into immediate quarantine. See full list on who.int